A research team from the College of Laser Engineering publishes a scientific research on the synergistic effect of silver nanoparticles.
A scientific team from the College of Laser and Optoelectronics Engineering at the University of Technology published a scientific research entitled: “The Synergistic Effect of Silver Nanoparticles Conjugated with the Antibiotic (Gentamicin): Inhibition of Multidrug Resistance, Bacterial Biofilm Formation, and Inhibition of the FimH Gene” in the journal Nano-Structures & Nano-Objects, a prestigious journal in the first quarter.
The research team included:-
- Prof. Dr. Karim Hussein Jawad
- Prof. Majed Sakhi Jaber
- Student Tabarak Muhammad Mahmoud.
The study examined the effect of silver nanoparticles (AgNPs) conjugated with the antibiotic gentamicin (Gent@AgNPs) in combating infections caused by resistant bacteria, such as Klebsiella pneumoniae and Proteus mirabilis, which cause urinary tract infections.
The study used laser ablation technology to produce these nanoparticles in an Eco- friendly manner. The results showed that combining silver nanoparticles with gentamicin enhanced the antibacterial activity. The study also demonstrated the ability of this combination to prevent biofilm formation on Foley catheters, indicating its potential as an effective therapeutic strategy to reduce the risk of infection and associated complications.
